Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, SORCS2 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible SORCS2-associated genes across cancer lineages are p62 Lck ligand, PTEN, and STAT3_pY705. Each is linked with SORCS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SORCS2-to-partner and partner-to-SORCS2 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (SORCS2→partner) and Y-score (partner→SORCS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.