Across TCGA cell cohorts, SORCS2 RNA expression is significantly associated with the RNA expression of many other genes, with 6,512 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SORCS2-associated genes across cancer lineages are C1R, RIN2, and ARHGAP23. Each is linked with SORCS2 in more than 7 cancer types. Because this analysis shows association rather than direction, both SORCS2-to-partner and partner-to-SORCS2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SORCS2→partner) and Y-score (partner→SORCS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	C1R →	+2.630	+1.943	<.001	.001	3	8
SKIN	RIN2 →	+2.423	+1.229	<.001	<.001	3	6
OESOPHAGUS	ARHGAP23 →	+2.282	+1.681	.006	.009	1	7
BREAST	ATP2B4 →	+1.530	+1.204	<.001	<.001	3	5
SKIN	DSE →	+2.024	+1.137	<.001	<.001	3	5
SKIN	EPHB2 →	+1.564	+0.959	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,512 associations by consensus.

Exploration

SORCS2 survival (RNA) · tumor vs normal (RNA) · all SORCS2 data types