SORBS1

Across TCGA cell cohorts, SORBS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,196 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SORBS1-associated GO terms across cancer lineages are Nucleosome assembly, Cellular response to nutrient levels, and Cytosolic transport. Each is linked with SORBS1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SORBS1-to-partner and partner-to-SORBS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleosome assembly grouped by SORBS1-low versus SORBS1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SORBS1→partner) and Y-score (partner→SORBS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Nucleosome assembly →	+0.097	+1.302	<.001	<.001	3	8
BLOOD_Myeloma	Cellular response to nutrient levels →	+0.035	+0.636	.003	.003	2	9
CNS	Cytosolic transport →	+0.056	+1.586	<.001	<.001	3	7
BREAST	Negative regulation of myoblast fusion →	+0.092	+0.895	<.001	.001	3	7
STOMACH	Epigenetic regulation of gene expression →	+0.057	+1.637	.003	.005	3	7
SOFT_TISSUE	Negative regulation of gene expression, epigenetic →	+0.043	+0.950	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,196 associations by consensus.

Nucleosome assembly by SORBS1 expression — BREAST

Explore this box plot interactively →