SOHLH2

Across TCGA cell cohorts, SOHLH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,823 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SOHLH2-associated GO terms across cancer lineages are Aerobic electron transport chain, ATP synthesis coupled electron transport, and Mitochondrial ATP synthesis coupled electron transport. Each is linked with SOHLH2 in more than 5 cancer types. Because this analysis shows association rather than direction, both SOHLH2-to-partner and partner-to-SOHLH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic electron transport chain grouped by SOHLH2-low versus SOHLH2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOHLH2→partner) and Y-score (partner→SOHLH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Aerobic electron transport chain →	+0.052	+0.384	.009	.007	3	6
BLOOD_Lymphoma	ATP synthesis coupled electron transport →	+0.044	+0.947	.007	.001	3	6
BLOOD_Lymphoma	Mitochondrial ATP synthesis coupled electron transport →	+0.044	+0.947	.007	.001	3	6
LUNG_NSCLC_LUAD	Response to cobalt ion →	+0.055	+1.029	.008	.009	3	5
LUNG_NSCLC_LUAD	Cellular respiration →	+0.039	+0.903	.005	.009	3	5
KIDNEY	Branched-chain amino acid metabolic process →	+0.091	+0.754	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,823 associations by consensus.

Aerobic electron transport chain by SOHLH2 expression — KIDNEY

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