SOHLH1

Across TCGA cell cohorts, SOHLH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 670 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SOHLH1-associated GO terms across cancer lineages are rRNA modification, RNA methylation, and Heme biosynthetic process. Each is linked with SOHLH1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SOHLH1-to-partner and partner-to-SOHLH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA modification grouped by SOHLH1-low versus SOHLH1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOHLH1→partner) and Y-score (partner→SOHLH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	rRNA modification →	+0.079	+0.083	.001	.005	3	4
BLOOD_Leukemia	RNA methylation →	+0.027	+0.016	.004	.005	2	4
BLOOD_Leukemia	Heme biosynthetic process →	+0.076	+0.020	<.001	.004	3	3
BLOOD_Leukemia	Mitochondrial tRNA modification →	+0.081	+0.030	<.001	.006	3	3
LUNG_NSCLC_LUAD	Regulation of osteoblast proliferation →	-0.114	-0.024	.001	.008	2	4
BONE	Negative regulation of chemotaxis →	-0.112	-0.090	.005	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 670 associations by consensus.

rRNA modification by SOHLH1 expression — BONE

Explore this box plot interactively →