SOHLH1

Across TCGA cell cohorts, SOHLH1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SOHLH1-associated genes across cancer lineages are RBMY1F, TGIF2LY, and OR2V2. Each is linked with SOHLH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SOHLH1-to-partner and partner-to-SOHLH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1F grouped by SOHLH1-low versus SOHLH1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOHLH1→partner) and Y-score (partner→SOHLH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RBMY1F →	+0.065	+5.022	<.001	.002	3	1
SKIN	TGIF2LY →	+0.239	+4.095	<.001	.009	3	1
SKIN	OR2V2 →	+0.019	+5.217	<.001	<.001	3	1
SKIN	MEIKIN →	+0.017	+4.415	<.001	.007	3	1
SKIN	AMELY →	+0.016	+4.415	.001	.007	3	1
LARGE_INTESTINE	PPP1R17 →	+0.055	+4.467	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

RBMY1F by SOHLH1 expression — SKIN

Explore this box plot interactively →