Across TCGA cell cohorts, SOGA3 mutation is significantly associated with the RNA expression of many other genes, with 715 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SOGA3-associated genes across cancer lineages are ODF1, TRMU, and RANGRF. Each is linked with SOGA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SOGA3-to-partner and partner-to-SOGA3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOGA3→partner) and Y-score (partner→SOGA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ODF1 →	+0.013	+4.022	<.001	.006	3	2
LARGE_INTESTINE	TRMU →	+0.492	+1.628	.002	.007	3	2
LARGE_INTESTINE	RANGRF →	+0.465	+3.321	.004	.002	3	2
LARGE_INTESTINE	LYG1 →	+0.723	+1.628	.001	.007	3	2
LARGE_INTESTINE	NAE1 →	+0.559	+2.000	<.001	.009	3	2
LARGE_INTESTINE	KANK3 →	+0.617	+1.800	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 715 associations by consensus.

Exploration

SOGA3 survival (RNA) · tumor vs normal (RNA) · all SOGA3 data types