SOGA1

Across TCGA patient cohorts, SOGA1 mutation is significantly associated with the RNA expression of many other genes, with 1,671 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SOGA1-associated genes across cancer lineages are DVL2, LELP1, and MIR1269A. Each is linked with SOGA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SOGA1-to-partner and partner-to-SOGA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DVL2 grouped by SOGA1-low versus SOGA1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOGA1→partner) and Y-score (partner→SOGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	DVL2 →	+0.499	+2.006	<.001	.005	3	3
BRCA	LELP1 →	+0.047	+5.281	<.001	.002	3	3
BRCA	MIR1269A →	+0.202	+4.386	.003	.008	3	3
BRCA	RNU6ATAC17P →	+0.528	+3.817	.003	.009	3	3
UCEC	HASPIN →	+0.560	+1.895	<.001	.001	3	3
UCEC	VPS18 →	+0.378	+1.584	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,671 associations by consensus.

DVL2 by SOGA1 expression — SKCM

Explore this box plot interactively →