SOGA1

Across TCGA cell cohorts, SOGA1 mutation is significantly associated with the RNA expression of many other genes, with 518 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SOGA1-associated genes across cancer lineages are OR7E24, ZMYND8, and ACBD5. Each is linked with SOGA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SOGA1-to-partner and partner-to-SOGA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E24 grouped by SOGA1-low versus SOGA1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOGA1→partner) and Y-score (partner→SOGA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR7E24 →	+0.029	+5.369	<.001	.004	3	2
LARGE_INTESTINE	ZMYND8 →	-0.671	-2.657	.004	.002	3	2
LARGE_INTESTINE	ACBD5 →	+0.709	+2.743	.003	.001	3	2
LARGE_INTESTINE	ABHD18 →	+0.532	+2.743	.001	.001	3	2
LARGE_INTESTINE	TSTD3 →	+0.433	+3.087	.001	.006	3	2
SOFT_TISSUE	PGK2 →	+0.209	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 518 associations by consensus.

OR7E24 by SOGA1 expression — SOFT_TISSUE

Explore this box plot interactively →