SOD3

Across TCGA cell cohorts, SOD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,753 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SOD3-associated GO terms across cancer lineages are Positive regulation of ruffle assembly, Viral process, and Regulation of protein localization to plasma membrane. Each is linked with SOD3 in more than 7 cancer types. Because this analysis shows association rather than direction, both SOD3-to-partner and partner-to-SOD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of ruffle assembly grouped by SOD3-low versus SOD3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOD3→partner) and Y-score (partner→SOD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of ruffle assembly →	+0.180	+2.403	<.001	<.001	3	8
BONE	Viral process →	+0.080	+1.907	<.001	<.001	3	8
BONE	Regulation of protein localization to plasma membrane →	+0.134	+2.513	<.001	<.001	3	8
BONE	Regulation of protein localization to membrane →	+0.069	+1.958	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Positive regulation of protein localization to membrane →	+0.077	+1.550	<.001	<.001	3	7
BONE	Viral life cycle →	+0.145	+2.852	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,753 associations by consensus.

Positive regulation of ruffle assembly by SOD3 expression — BONE

Explore this box plot interactively →