Across TCGA pan-cancer cohorts, SOD1P1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SOD1P1’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where SOD1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SOD1P1 is over-expressed in tumor.
LIHC are the cancer types where SOD1P1 tumor–normal differential expression is most reproducible.