SOCS5P3

Across TCGA pan-cancer cohorts, SOCS5P3 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated SOCS5P3 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SOCS5P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SOCS5P3 expression acts as an unfavorable survival marker, although some lineages such as CESC and HNSC show a favorable association.

ACC, READ, and KIRC are the cancer types where SOCS5P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.114	0.892	<.001	42	view →
READ	OS	Tertile	All	0.166	0.830	<.001	36	view →
KIRC	OS	Tertile	All	0.742	0.829	.010	31	view →
MESO	DFS	Tertile	II,III,IV	0.200	0.424	.022	27	view →
CESC	DFS	Tertile	All	0.928	0.806	.029	24	view →
LIHC	DFS	Tertile	All	0.339	0.539	.033	24	view →
COAD	DFS	Tertile	IV	0.271	0.501	.019	18	view →
HNSC	OS	Tertile	All	0.568	0.333	.026	15	view →
UCEC	OS	Quartile	All	0.886	0.938	.016	14	view →
CHOL	DFS	Tertile	II,III,IV	0.114	0.502	.048	9	view →
BLCA	OS	Tertile	II,III,IV	0.807	0.694	.042	6	view →
GBM	OS	Tertile	All	0.325	0.439	.035	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

SOCS5P3–ACC (OS)

Open the ACC breakdown →