SOCS5

Across TCGA cell cohorts, SOCS5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,467 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SOCS5-associated GO terms across cancer lineages are Positive regulation of pinocytosis, Regulation of angiotensin-activated signaling pathway, and Positive regulation of translational initiation. Each is linked with SOCS5 in more than 12 cancer types. Because this analysis shows association rather than direction, both SOCS5-to-partner and partner-to-SOCS5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of pinocytosis grouped by SOCS5-low versus SOCS5-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOCS5→partner) and Y-score (partner→SOCS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of pinocytosis →	+0.128	+1.076	.002	<.001	3	13
SKIN	Regulation of angiotensin-activated signaling pathway →	+0.224	+0.892	.004	<.001	2	13
PANCREAS	Positive regulation of translational initiation →	+0.092	+0.611	.001	.001	3	12
BONE	Response to hydrostatic pressure →	+0.174	+0.834	<.001	<.001	3	12
BREAST	Regulation of cytokinesis →	+0.074	+1.028	.001	<.001	3	11
OVARY	Phosphatidylinositol biosynthetic process →	+0.046	+0.531	.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,467 associations by consensus.

Positive regulation of pinocytosis by SOCS5 expression — URINARY_TRACT

Explore this box plot interactively →