SOCS2

Across TCGA patient cohorts, SOCS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,299 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SOCS2-associated proteins across cancer lineages are NID2, RASIP1_S41, and CD34. Each is linked with SOCS2 in more than 7 cancer types. Because this analysis shows association rather than direction, both SOCS2-to-partner and partner-to-SOCS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOCS2 versus NID2 in OV, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOCS2→partner) and Y-score (partner→SOCS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NID2 →	+0.537	+0.600	<.001	.004	3	8
CCRCC	RASIP1_S41 →	+0.599	+1.027	<.001	<.001	3	7
CCRCC	CD34 →	+0.803	+1.240	<.001	<.001	3	7
UCEC	TNS2_S648 →	+0.844	+1.259	<.001	<.001	3	7
UCEC	PPM1F →	+0.343	+0.959	<.001	<.001	3	7
UCEC	CNRIP1 →	+0.789	+1.170	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,299 associations by consensus.

SOCS2 vs NID2 — OV

Explore this scatter interactively →