Across TCGA patient cohorts, SOCS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,510 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SOCS1-associated proteins across cancer lineages are PTPRC, GBP4, and ITGAL. Each is linked with SOCS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SOCS1-to-partner and partner-to-SOCS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOCS1→partner) and Y-score (partner→SOCS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PTPRC →	+0.771	+1.073	.001	<.001	3	8
BRCA	GBP4 →	+0.674	+0.931	<.001	<.001	3	7
BRCA	ITGAL →	+0.627	+0.927	<.001	<.001	3	7
BRCA	LCP2 →	+0.495	+1.021	<.001	<.001	3	7
BRCA	APOBEC3G →	+0.580	+0.888	<.001	<.001	3	7
BRCA	APOL3 →	+0.666	+0.919	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,510 associations by consensus.

Exploration

SOCS1 survival (RNA) · tumor vs normal (RNA) · all SOCS1 data types