SOCAR

Across TCGA patient cohorts, SOCAR RNA expression is significantly associated with the protein abundance of many other proteins, with 9,164 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SOCAR-associated proteins across cancer lineages are QKI, DOK2, and PPP1R18. Each is linked with SOCAR in more than 5 cancer types. Because this analysis shows association rather than direction, both SOCAR-to-partner and partner-to-SOCAR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOCAR versus QKI in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOCAR→partner) and Y-score (partner→SOCAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	QKI →	+0.312	+0.416	<.001	<.001	3	6
BRCA	DOK2 →	+0.566	+0.484	<.001	<.001	3	6
OV	PPP1R18 →	+0.447	+0.322	<.001	<.001	3	5
OV	PPP1R18_S224 →	+0.970	+0.357	<.001	<.001	3	5
UCEC	CORO1A →	+0.678	+0.406	<.001	<.001	3	5
OV	DOCK2 →	+0.524	+0.289	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,164 associations by consensus.

SOCAR vs QKI — BRCA

Explore this scatter interactively →