SOBP

Across TCGA cell cohorts, SOBP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,160 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SOBP-associated GO terms across cancer lineages are Protein-DNA complex organization, Positive regulation of sodium ion transmembrane transport, and Sodium ion export across plasma membrane. Each is linked with SOBP in more than 11 cancer types. Because this analysis shows association rather than direction, both SOBP-to-partner and partner-to-SOBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex organization grouped by SOBP-low versus SOBP-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOBP→partner) and Y-score (partner→SOBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein-DNA complex organization →	+0.077	+0.490	<.001	<.001	3	12
STOMACH	Positive regulation of sodium ion transmembrane transport →	-0.306	-1.292	<.001	<.001	3	11
LARGE_INTESTINE	Sodium ion export across plasma membrane →	-0.231	-0.726	<.001	<.001	3	11
LARGE_INTESTINE	Positive regulation of monoatomic ion transport →	-0.097	-0.807	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA repair →	+0.058	+0.381	<.001	.004	3	11
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.078	+0.360	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,160 associations by consensus.

Protein-DNA complex organization by SOBP expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →