SOAT2

Across TCGA cell cohorts, SOAT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,667 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible SOAT2-associated GO terms across cancer lineages are Regulation of intestinal cholesterol absorption, Positive regulation of intestinal cholesterol absorption, and Mammary gland morphogenesis. Each is linked with SOAT2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SOAT2-to-partner and partner-to-SOAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intestinal cholesterol absorption grouped by SOAT2-low versus SOAT2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOAT2→partner) and Y-score (partner→SOAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of intestinal cholesterol absorption →	-0.452	-2.613	<.001	.002	3	7
LIVER	Positive regulation of intestinal cholesterol absorption →	-0.283	-2.622	.001	.002	3	7
SOFT_TISSUE	Mammary gland morphogenesis →	+0.133	+0.059	<.001	.007	3	6
STOMACH	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.060	+0.082	.009	.007	2	7
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.094	+0.479	<.001	.008	3	5
OVARY	Regulation of plasma membrane repair →	+0.154	+0.104	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,667 associations by consensus.

Regulation of intestinal cholesterol absorption by SOAT2 expression — LIVER

Explore this box plot interactively →