SNX8

Across TCGA pan-cancer cohorts, SNX8 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SNX8 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SNX8 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNX8 expression acts as an unfavorable survival marker.

CCRCC, UCEC, and HNSC are the cancer types where SNX8 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	III,IV	0.205	0.691	.003	44	view →
UCEC	DFS	Median	All	0.790	0.928	.029	10	view →
HNSC	DFS	Median	III,IV	0.532	0.752	.024	5	view →
LSCC	OS	Median	All	0.793	1.000	.025	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SNX8–CCRCC (DFS)

Open the CCRCC breakdown →