SNX8

Across TCGA patient cohorts, SNX8 RNA expression is significantly associated with the mutation status of many other genes, with 8,380 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX8-associated genes across cancer lineages are TP53, LAMA1, and PCLO. Each is linked with SNX8 in more than 9 cancer types. Because this analysis shows association rather than direction, both SNX8-to-partner and partner-to-SNX8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by SNX8-low versus SNX8-high in LIHC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX8→partner) and Y-score (partner→SNX8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TP53 →	+1.570	+0.653	<.001	<.001	3	10
LUAD	LAMA1 →	+1.680	+0.376	.006	.003	3	6
UCEC	PCLO →	+1.162	+0.292	<.001	<.001	3	6
UCEC	PIKFYVE →	+1.267	+0.318	<.001	.001	3	5
LGG	TTN →	+1.460	+0.175	.004	.001	2	5
LGG	EGFR →	+2.534	+0.358	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,380 associations by consensus.

TP53 by SNX8 expression — LIHC

Explore this box plot interactively →