SNX8

Across TCGA patient cohorts, SNX8 protein abundance is significantly associated with the RNA expression of many other genes, with 11,670 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNX8-associated genes across cancer lineages are LGALS1, YKT6, and KDELR2. Each is linked with SNX8 in more than 4 cancer types. Because this analysis shows association rather than direction, both SNX8-to-partner and partner-to-SNX8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX8 versus LGALS1 in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX8→partner) and Y-score (partner→SNX8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LGALS1 →	+1.048	+0.379	<.001	<.001	3	5
LSCC	YKT6 →	+0.457	+0.193	<.001	.004	3	5
OV	KDELR2 →	+0.653	+0.358	.001	.002	3	5
OV	PSMG3 →	+0.539	+0.283	.005	.004	3	5
OV	H3-3A →	-0.460	-0.252	<.001	<.001	3	5
OV	FRAT2 →	-0.623	-0.284	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,670 associations by consensus.

SNX8 vs LGALS1 — LSCC

Explore this scatter interactively →