SNX8

Across TCGA cell cohorts, SNX8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,182 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SNX8-associated GO terms across cancer lineages are Deactivation of mitotic spindle assembly checkpoint, Early endosome to Golgi transport, and Regulation of hippo signaling. Each is linked with SNX8 in more than 14 cancer types. Because this analysis shows association rather than direction, both SNX8-to-partner and partner-to-SNX8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Deactivation of mitotic spindle assembly checkpoint grouped by SNX8-low versus SNX8-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX8→partner) and Y-score (partner→SNX8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Deactivation of mitotic spindle assembly checkpoint →	+0.175	+0.959	<.001	<.001	3	15
BLOOD_Lymphoma	Early endosome to Golgi transport →	+0.108	+1.295	<.001	<.001	3	13
BONE	Regulation of hippo signaling →	+0.094	+0.999	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.201	+0.987	<.001	<.001	3	10
STOMACH	Caveolin-mediated endocytosis →	+0.135	+1.035	.002	.004	1	12
LARGE_INTESTINE	Regulation of Golgi inheritance →	+0.136	+1.287	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,182 associations by consensus.

Deactivation of mitotic spindle assembly checkpoint by SNX8 expression — SKIN

Explore this box plot interactively →