SNX8

Across TCGA cell cohorts, SNX8 protein abundance is significantly associated with the RNA expression of many other genes, with 2,410 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SNX8-associated genes across cancer lineages are PPARGC1B, MCUB, and HIRIP3. Each is linked with SNX8 in more than 6 cancer types. Because this analysis shows association rather than direction, both SNX8-to-partner and partner-to-SNX8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX8 versus PPARGC1B in CNS, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX8→partner) and Y-score (partner→SNX8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	PPARGC1B →	+0.821	+0.662	.006	.007	3	7
OVARY	MCUB →	-1.126	-0.645	.003	.003	3	7
BREAST	HIRIP3 →	-1.031	-0.779	.001	<.001	3	6
PANCREAS	FBXL5 →	-0.841	-0.488	.003	.008	3	5
BLOOD_Leukemia	RAD51 →	-0.591	-0.471	.006	.008	3	5
OESOPHAGUS	FAM169A →	+1.519	+0.852	.003	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,410 associations by consensus.

SNX8 vs PPARGC1B — CNS

Explore this scatter interactively →