SNX7

Across TCGA patient cohorts, SNX7 mutation is significantly associated with the RNA expression of many other genes, with 1,209 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX7-associated genes across cancer lineages are MTND2P2, RNU6-1170P, and MIR4771-2. Each is linked with SNX7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX7-to-partner and partner-to-SNX7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND2P2 grouped by SNX7-low versus SNX7-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX7→partner) and Y-score (partner→SNX7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MTND2P2 →	+0.066	+3.754	.002	.003	3	2
LUSC	RNU6-1170P →	+0.426	+3.438	.001	.006	3	2
LUSC	MIR4771-2 →	+0.711	+3.735	.001	.006	3	2
BLCA	VN1R91P →	+0.199	+4.562	<.001	.006	3	2
BLCA	MIR7849 →	+0.517	+4.423	<.001	.002	3	2
LIHC	RNA5SP308 →	+0.470	+4.758	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,209 associations by consensus.

MTND2P2 by SNX7 expression — LUSC

Explore this box plot interactively →