SNX7

Across TCGA cell cohorts, SNX7 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNX7-associated genes across cancer lineages are ZCCHC2, ATP5F1A, and TADA3. Each is linked with SNX7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX7-to-partner and partner-to-SNX7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZCCHC2 grouped by SNX7-low versus SNX7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX7→partner) and Y-score (partner→SNX7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZCCHC2 →	+1.048	+3.067	<.001	.009	3	1
LARGE_INTESTINE	ATP5F1A →	+0.932	+3.082	.001	.007	3	1
LARGE_INTESTINE	TADA3 →	+0.496	+3.137	.002	.007	3	1
LARGE_INTESTINE	TNK1 →	+0.871	+3.064	.002	.009	3	1
LARGE_INTESTINE	C4orf47 →	+0.444	+3.371	<.001	.004	3	1
LARGE_INTESTINE	CD300H →	+0.024	+3.415	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

ZCCHC2 by SNX7 expression — LARGE_INTESTINE

Explore this box plot interactively →