SNX33

Across TCGA patient cohorts, SNX33 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,275 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SNX33-associated proteins across cancer lineages are SMAD3, SEC11C, and UBE2J1. Each is linked with SNX33 in more than 5 cancer types. Because this analysis shows association rather than direction, both SNX33-to-partner and partner-to-SNX33 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX33 versus SMAD3 in LUAD, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX33→partner) and Y-score (partner→SNX33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SMAD3 →	+0.491	+0.530	<.001	<.001	3	6
LSCC	SEC11C →	-0.627	-0.319	<.001	<.001	3	5
LSCC	UBE2J1 →	-0.497	-0.512	.001	<.001	3	5
UCEC	FBLIM1 →	+0.363	+0.508	<.001	<.001	3	4
OV	SRP19 →	-0.640	-0.576	<.001	.006	3	4
BRCA	SRP68 →	-0.270	-0.409	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,275 associations by consensus.

SNX33 vs SMAD3 — LUAD

Explore this scatter interactively →