SNX33

Across TCGA patient cohorts, SNX33 protein abundance is significantly associated with the RNA expression of many other genes, with 10,444 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SNX33-associated genes across cancer lineages are NEK2, CENPF, and CDC25A. Each is linked with SNX33 in more than 5 cancer types. Because this analysis shows association rather than direction, both SNX33-to-partner and partner-to-SNX33 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX33 versus NEK2 in LUAD, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX33→partner) and Y-score (partner→SNX33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NEK2 →	-0.993	-0.158	<.001	<.001	3	6
UCEC	CENPF →	-1.064	-0.222	<.001	<.001	3	6
LUAD	CDC25A →	-0.870	-0.242	<.001	<.001	3	6
UCEC	LHFPL6 →	+0.730	+0.197	<.001	<.001	3	6
UCEC	ADAMTS9-AS2 →	+0.935	+0.202	<.001	<.001	3	6
UCEC	PTH1R →	+0.756	+0.191	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,444 associations by consensus.

SNX33 vs NEK2 — LUAD

Explore this scatter interactively →