SNX32

Across TCGA patient cohorts, SNX32 mutation is significantly associated with the RNA expression of many other genes, with 2,969 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX32-associated genes across cancer lineages are VDAC1P6, RNU6-502P, and LMF2. Each is linked with SNX32 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX32-to-partner and partner-to-SNX32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VDAC1P6 grouped by SNX32-low versus SNX32-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX32→partner) and Y-score (partner→SNX32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	VDAC1P6 →	+0.163	+3.444	.002	.006	3	2
LUSC	RNU6-502P →	+0.324	+5.093	.002	.008	3	2
UCEC	LMF2 →	+0.399	+3.040	.002	<.001	3	2
UCEC	RHBDD3 →	+0.451	+3.000	<.001	<.001	3	2
UCEC	AP1B1 →	+0.530	+2.284	<.001	<.001	3	2
UCEC	MCM5 →	+0.585	+2.928	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,969 associations by consensus.

VDAC1P6 by SNX32 expression — SKCM

Explore this box plot interactively →