SNX32

Across TCGA cell cohorts, SNX32 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SNX32-associated genes across cancer lineages are GHRHR, SCGB1D4, and GLI3. Each is linked with SNX32 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX32-to-partner and partner-to-SNX32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRHR grouped by SNX32-low versus SNX32-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX32→partner) and Y-score (partner→SNX32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GHRHR →	+0.259	+3.442	<.001	<.001	3	2
OVARY	SCGB1D4 →	+0.130	+5.807	<.001	.001	3	1
BLOOD_Leukemia	GLI3 →	+1.778	+3.266	<.001	.007	3	1
BLOOD_Leukemia	PLEKHG4B →	+2.345	+3.449	<.001	.003	3	1
BLOOD_Leukemia	SAXO1 →	+0.034	+3.781	.001	.002	3	1
BLOOD_Leukemia	ONECUT1 →	+0.753	+3.418	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

GHRHR by SNX32 expression — BLOOD_Leukemia

Explore this box plot interactively →