SNX31

Across TCGA pan-cancer cohorts, SNX31 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SNX31 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SNX31 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated SNX31 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

UCEC, LUAD, and PRAD are the cancer types where SNX31 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.627	.013	28	view →
LUAD	OS	Median	II,III,IV	0.502	0.751	<.001	14	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
SKCM	DFS	Median	III,IV	0.730	0.239	.029	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SNX31–UCEC (DFS)

Open the UCEC breakdown →