SNX31

Across TCGA cell cohorts, SNX31 RNA expression is significantly associated with the go_rna of many other GO terms, with 805 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible SNX31-associated GO terms across cancer lineages are Negative regulation of mRNA metabolic process, Negative regulation of intrinsic apoptotic signaling pathway, and Negative regulation of stem cell differentiation. Each is linked with SNX31 in more than 5 cancer types. Because this analysis shows association rather than direction, both SNX31-to-partner and partner-to-SNX31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA metabolic process grouped by SNX31-low versus SNX31-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX31→partner) and Y-score (partner→SNX31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of mRNA metabolic process →	+0.050	+0.080	<.001	.006	3	6
PANCREAS	Negative regulation of intrinsic apoptotic signaling pathway →	+0.046	+0.094	.003	.001	3	5
URINARY_TRACT	Negative regulation of stem cell differentiation →	+0.113	+1.519	.001	.001	3	5
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.072	+0.118	.006	.006	3	5
BLOOD_Lymphoma	Mitochondrial potassium ion transmembrane transport →	-0.082	-0.056	<.001	.006	3	4
PANCREAS	Protein polyufmylation →	+0.092	+0.100	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 805 associations by consensus.

Negative regulation of mRNA metabolic process by SNX31 expression — PANCREAS

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