SNX30

Across TCGA pan-cancer cohorts, SNX30 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SNX30 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SNX30 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SNX30 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LUAD, and HNSC are the cancer types where SNX30 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	0.958	0.708	.010	33	view →
LUAD	OS	Quartile	II,III,IV	0.699	0.231	.001	21	view →
HNSC	OS	Tertile	IV	0.876	0.637	.010	13	view →
PDAC	OS	Tertile	III,IV	0.599	0.135	.009	9	view →
UCEC	OS	Tertile	All	1.000	0.847	.011	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SNX30–CCRCC (OS)

Open the CCRCC breakdown →