SNX30

Across TCGA patient cohorts, SNX30 mutation is significantly associated with the RNA expression of many other genes, with 1,335 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX30-associated genes across cancer lineages are GOLGA2P3Y, RNU6ATAC30P, and RNA5SP247. Each is linked with SNX30 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX30-to-partner and partner-to-SNX30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GOLGA2P3Y grouped by SNX30-low versus SNX30-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX30→partner) and Y-score (partner→SNX30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GOLGA2P3Y →	+0.038	+6.240	<.001	<.001	3	2
HNSC	RNU6ATAC30P →	+0.380	+4.245	.003	.008	3	2
UCEC	RNA5SP247 →	+0.370	+2.042	.008	.004	3	2
UCEC	ZFP91-CNTF →	+0.028	+2.031	<.001	.007	3	2
BLCA	TRAJ30 →	+0.607	+5.484	<.001	<.001	3	2
HNSC	RARRES2P5 →	+0.182	+4.346	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,335 associations by consensus.

GOLGA2P3Y by SNX30 expression — HNSC

Explore this box plot interactively →