SNX24

Across TCGA pan-cancer cohorts, SNX24 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SNX24 data layer compared with 29 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SNX24 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNX24 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

PDAC, CCRCC, and LUAD are the cancer types where SNX24 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.672	0.847	.005	21	view →
CCRCC	DFS	Quartile	II,III,IV	1.000	0.064	.024	18	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	3	view →
HNSC	DFS	Tertile	All	0.909	0.708	.047	1	view →
LSCC	DFS	Median	II,III,IV	0.871	0.683	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SNX24–PDAC (DFS)

Open the PDAC breakdown →