SNX24

Across TCGA patient cohorts, SNX24 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX24-associated genes across cancer lineages are Caspase-7-cleavedD198, A-Raf_pS299, and HSP70. Each is linked with SNX24 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX24-to-partner and partner-to-SNX24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by SNX24-low versus SNX24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX24→partner) and Y-score (partner→SNX24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.944	+3.019	.002	.019	3	2
UCEC	A-Raf_pS299 →	-0.132	-3.000	.034	.036	3	1
UCEC	HSP70 →	-0.469	-3.321	.025	.010	3	1
UCEC	PCNA →	+0.314	+3.000	.005	.036	3	1
UCEC	ATM →	-0.733	-3.321	.002	.010	3	1
UCEC	14-3-3_beta →	-0.133	-2.979	.011	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Caspase-7-cleavedD198 by SNX24 expression — UCEC

Explore this box plot interactively →