SNX20

Across TCGA cell cohorts, SNX20 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,596 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SNX20-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Vacuole fusion, and SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Each is linked with SNX20 in more than 5 cancer types. Because this analysis shows association rather than direction, both SNX20-to-partner and partner-to-SNX20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SNX20-low versus SNX20-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX20→partner) and Y-score (partner→SNX20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of myoblast fusion →	+0.084	+0.022	<.001	.003	3	6
OESOPHAGUS	Vacuole fusion →	+0.087	+0.051	<.001	.007	3	5
PANCREAS	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.040	+0.025	.001	<.001	2	6
PANCREAS	Negative regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.119	+0.031	<.001	<.001	3	5
PANCREAS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.065	+0.017	.001	.002	3	5
LUNG_SCLC	Glycerolipid biosynthetic process →	+0.037	+0.083	<.001	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,596 associations by consensus.

Negative regulation of myoblast fusion by SNX20 expression — PANCREAS

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