SNX19

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNX19 mutation is significantly associated with the RNA expression of many other genes, with 5,038 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX19-associated genes across cancer lineages are RN7SL134P, CMC2, and FAM192BP. Each is linked with SNX19 in more than 3 cancer types. Because this analysis shows association rather than direction, both SNX19-to-partner and partner-to-SNX19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by SNX19-low versus SNX19-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX19→partner) and Y-score (partner→SNX19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCRN7SL134P →+0.176+4.451<.001.00634
UCECCMC2 →+0.476+1.954<.001<.00134
UCECFAM192BP →+0.218+1.380.002.00434
SKCMTRIM37 →+0.727+3.472.001.00234
READIGHD5-12 →+1.742+5.421<.001.00533
UCECTMEM62 →+0.520+2.032<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,038 associations by consensus.

RN7SL134P by SNX19 expression — LIHC

Box plot of RN7SL134P in SNX19-low vs SNX19-high samples in LIHC.

Explore this box plot interactively →

Exploration