SNX19

Across TCGA patient cohorts, SNX19 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX19-associated genes across cancer lineages are ASNS, Ku80, and TFRC. Each is linked with SNX19 in more than 3 cancer types. Because this analysis shows association rather than direction, both SNX19-to-partner and partner-to-SNX19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by SNX19-low versus SNX19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX19→partner) and Y-score (partner→SNX19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.427	+1.662	<.001	.010	3	4
UCEC	Ku80 →	+0.213	+1.536	.004	.005	3	3
UCEC	TFRC →	+0.548	+2.700	.001	.005	3	3
COAD	Caspase-7-cleavedD198 →	+1.218	+2.815	.004	.036	3	2
UCEC	14-3-3_beta →	-0.085	-1.510	.008	.008	3	2
UCEC	ACC1 →	+0.297	+2.598	.010	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

ASNS by SNX19 expression — UCEC

Explore this box plot interactively →