Across TCGA pan-cancer cohorts, SNX18P8 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SNX18P8’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where SNX18P8 RNA is repressed in tumor relative to normal tissue. In most cancer types SNX18P8 is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.
COAD and THCA are the cancer types where SNX18P8 tumor–normal differential expression is most reproducible.