Across TCGA pan-cancer cohorts, SNX18P25 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SNX18P25’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SNX18P25 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNX18P25 is over-expressed in tumor.
KIRC and LIHC are the cancer types where SNX18P25 tumor–normal differential expression is most reproducible.