SNX18P23

Across TCGA patient cohorts, SNX18P23 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,824 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SNX18P23-associated GO terms across cancer lineages are Protein quality control for misfolded or incompletely synthesized proteins, DNA replication, and tRNA metabolic process. Each is linked with SNX18P23 in more than 11 cancer types. Because this analysis shows association rather than direction, both SNX18P23-to-partner and partner-to-SNX18P23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein quality control for misfolded or incompletely synthesized proteins grouped by SNX18P23-low versus SNX18P23-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX18P23→partner) and Y-score (partner→SNX18P23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Protein quality control for misfolded or incompletely synthesized proteins →	+0.090	+0.042	<.001	.002	3	12
ESCA	DNA replication →	+0.101	+0.044	<.001	.006	2	12
ESCA	tRNA metabolic process →	+0.090	+0.049	<.001	.007	3	11
STAD	Endoplasmic reticulum organization →	+0.070	+0.063	<.001	<.001	3	11
ESCA	tRNA processing →	+0.088	+0.058	<.001	.003	3	11
ESCA	RNA modification →	+0.092	+0.076	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,824 associations by consensus.

Protein quality control for misfolded or incompletely synthesized proteins by SNX18P23 expression — ESCA

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