Across TCGA pan-cancer cohorts, SNX18P14 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SNX18P14’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where SNX18P14 RNA is repressed in tumor relative to normal tissue. In most cancer types SNX18P14 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA, KIRP, and KIRC are the cancer types where SNX18P14 tumor–normal differential expression is most reproducible.