SNX18P12

Across TCGA pan-cancer cohorts, SNX18P12 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated SNX18P12 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SNX18P12 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNX18P12 expression acts as an unfavorable survival marker, although some lineages such as STAD and DLBC show a favorable association.

HNSC, LGG, and READ are the cancer types where SNX18P12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	0.317	0.579	.010	30	view →
LGG	OS	Tertile	All	0.848	0.914	.003	23	view →
READ	DFS	Tertile	III,IV	0.176	0.768	<.001	18	view →
LIHC	DFS	Quartile	All	0.417	0.598	.002	18	view →
KIRP	DFS	Quartile	All	0.475	0.613	.011	17	view →
KIRC	DFS	Median	All	0.570	0.712	.011	15	view →
UVM	OS	Median	III,IV	0.304	1.000	.008	15	view →
STAD	DFS	Quartile	III,IV	0.577	0.267	.009	12	view →
LUAD	DFS	Tertile	IV	0.447	0.976	.045	12	view →
COAD	DFS	Tertile	III,IV	0.346	0.559	.027	9	view →
PCPG	DFS	Tertile	All	0.853	0.954	.024	7	view →
CHOL	OS	Tertile	III,IV	0.290	0.855	.027	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

SNX18P12–HNSC (DFS)

Open the HNSC breakdown →