SNX18

Across TCGA patient cohorts, SNX18 mutation is significantly associated with the RNA expression of many other genes, with 4,994 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX18-associated genes across cancer lineages are RN7SL447P, SNRPGP7, and MIR548AW. Each is linked with SNX18 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNX18-to-partner and partner-to-SNX18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL447P grouped by SNX18-low versus SNX18-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX18→partner) and Y-score (partner→SNX18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL447P →	+0.203	+5.201	<.001	.007	3	3
COAD	SNRPGP7 →	+0.218	+3.017	.001	.009	3	3
UCEC	MIR548AW →	+0.168	+2.785	<.001	.008	3	3
UCEC	LINC02084 →	+0.355	+2.555	<.001	<.001	3	2
UCEC	IGHV2-70 →	+1.427	+1.807	<.001	<.001	3	2
UCEC	SYNRG →	+0.322	+3.043	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,994 associations by consensus.

RN7SL447P by SNX18 expression — CESC

Explore this box plot interactively →