SNX18

Across TCGA cell cohorts, SNX18 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,460 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SNX18-associated GO terms across cancer lineages are Response to rapamycin, Cellular response to rapamycin, and Plasma membrane tubulation. Each is linked with SNX18 in more than 10 cancer types. Because this analysis shows association rather than direction, both SNX18-to-partner and partner-to-SNX18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to rapamycin grouped by SNX18-low versus SNX18-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX18→partner) and Y-score (partner→SNX18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Response to rapamycin →	+0.152	+0.961	<.001	<.001	3	10
BREAST	Cellular response to rapamycin →	+0.134	+0.906	<.001	<.001	3	10
URINARY_TRACT	Plasma membrane tubulation →	+0.094	+0.992	.006	.004	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of TORC2 signaling →	+0.076	+0.881	.006	.002	3	10
OVARY	Cellular response to epidermal growth factor stimulus →	+0.092	+0.766	.001	.002	2	11
LARGE_INTESTINE	Positive regulation of cellular response to transforming growth factor beta stimulus →	+0.106	+1.132	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,460 associations by consensus.

Response to rapamycin by SNX18 expression — BREAST

Explore this box plot interactively →