SNX17

Across TCGA patient cohorts, SNX17 mutation is significantly associated with the RNA expression of many other genes, with 929 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX17-associated genes across cancer lineages are MTCO2P31, SNORD90, and RNU6-1213P. Each is linked with SNX17 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNX17-to-partner and partner-to-SNX17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTCO2P31 grouped by SNX17-low versus SNX17-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX17→partner) and Y-score (partner→SNX17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MTCO2P31 →	+0.053	+4.736	.004	.007	3	3
UCEC	SNORD90 →	+0.269	+2.032	<.001	.007	3	2
UCEC	RNU6-1213P →	+0.189	+3.374	<.001	.003	3	2
STAD	TCERG1L-AS1 →	+0.464	+3.415	<.001	.009	3	2
BRCA	MIR6507 →	+0.359	+8.055	<.001	.007	3	1
BRCA	RPPH1-2P →	+0.103	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 929 associations by consensus.

MTCO2P31 by SNX17 expression — HNSC

Explore this box plot interactively →