SNX17

Across TCGA cell cohorts, SNX17 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,398 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SNX17-associated GO terms across cancer lineages are Regulation of female receptivity, Regulation of DNA damage checkpoint, and Tissue homeostasis. Each is linked with SNX17 in more than 10 cancer types. Because this analysis shows association rather than direction, both SNX17-to-partner and partner-to-SNX17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of female receptivity grouped by SNX17-low versus SNX17-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX17→partner) and Y-score (partner→SNX17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of female receptivity →	+1.346	+0.487	<.001	.002	2	11
LARGE_INTESTINE	Regulation of DNA damage checkpoint →	+0.056	+0.369	.002	.001	3	10
SKIN	Tissue homeostasis →	-0.053	-0.485	.001	.001	3	9
CNS	Negative regulation of bicellular tight junction assembly →	+0.130	+0.618	<.001	<.001	3	9
SKIN	Anatomical structure homeostasis →	-0.053	-0.485	.001	.001	3	9
LUNG_SCLC	Cholesterol catabolic process →	+0.322	+0.823	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,398 associations by consensus.

Regulation of female receptivity by SNX17 expression — LIVER

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