SNX14

Across TCGA pan-cancer cohorts, SNX14 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SNX14 data layer compared with 23 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SNX14 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SNX14 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where SNX14 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	1.000	0.899	.008	11	view →
HNSC	DFS	Tertile	IV	0.826	0.481	.013	8	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	8	view →
PDAC	OS	Median	IV	0.405	0.828	.038	6	view →
LSCC	DFS	Quartile	II,III,IV	0.187	0.766	.024	4	view →
GBM	OS	Median	All	0.679	0.847	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SNX14–CCRCC (OS)

Open the CCRCC breakdown →