SNX14

Across TCGA patient cohorts, SNX14 protein abundance is significantly associated with the RNA expression of many other genes, with 5,620 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SNX14-associated genes across cancer lineages are YKT6, LYPLA2, and RAC1. Each is linked with SNX14 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNX14-to-partner and partner-to-SNX14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX14 versus YKT6 in LUAD, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX14→partner) and Y-score (partner→SNX14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	YKT6 →	+0.548	+0.294	.002	<.001	3	3
LUAD	LYPLA2 →	+0.575	+0.239	<.001	.003	3	3
OV	RAC1 →	+0.438	+0.245	<.001	<.001	3	3
CCRCC	ATIC →	-0.497	-0.181	<.001	.003	3	3
OV	RBAK →	+0.445	+0.269	<.001	<.001	3	3
LUAD	ZNF12 →	+0.401	+0.245	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,620 associations by consensus.

SNX14 vs YKT6 — LUAD

Explore this scatter interactively →