SNX13

Across TCGA patient cohorts, SNX13 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX13-associated genes across cancer lineages are eEF2, GAPDH, and ATM. Each is linked with SNX13 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNX13-to-partner and partner-to-SNX13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by SNX13-low versus SNX13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX13→partner) and Y-score (partner→SNX13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.281	+2.222	.010	.009	3	3
COAD	GAPDH →	+0.655	+2.330	.004	.020	3	3
COAD	ATM →	-0.720	-3.321	<.001	.009	3	3
COAD	Src →	-0.206	-2.313	.019	.035	3	3
COAD	eIF4E →	+0.294	+3.182	<.001	.009	3	2
UCEC	JNK_pT183_Y185 →	-0.150	-2.169	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

eEF2 by SNX13 expression — UCEC

Explore this box plot interactively →